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Two genome-wide linkage disequilibrium screens in Scandinavian multiple sclerosis patients

Hanne F Harbo1, Pameli Datta, Annette Oturai

  • 1Institute of Immunology, Rikshospitalet University Hospital, 0027 Oslo, Norway. h.f.harbo@labmed.uio.no

Journal of Neuroimmunology
|October 25, 2003
PubMed

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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