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[Thin-layer cytology in endometrial diagnosis]
A M Buccoliero1, A Caldarella, I Noci
1Dipartimento di Patologia Umana e Oncologia, Università di Firenze, viale G.B. Morgagni 85, 50134 Firenze. ambuccoliero@unifi.it
Abstract:
Our purpose was to test the liquid-based thin layer method on the endometrial cytology. One hundred sixty two consecutive patients before the hysterectomy (55 women because of various causes; 107 asymptomatic postmenopausal women because of prolapsed uterus) had the endometrial cytology (all women) and the biopsy (107 postmenopausal women prolapsed uterus affected). Cytohistologic concordance was 98%: all endometrial neoplasms and atypical hyperplasia (10 cases) and 15 of the 18 (83%) simple hyperplasias were diagnosed by thin layer endometrial cytology. In asymptomatic postmenopausal women cytology gave sufficient material for the diagnosis significantively more often than endometrial biopsy (respectively 82% and 24%; p = 0.000).