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Primary embryonal rhabdomyosarcoma of prostate in adults: diagnosis and management
1Department of Urology, All India Institute of Medical Sciences, New Delhi-29, India. nabeeghlolam@hotmail.com
Insights
Prostate embryonal rhabdomyosarcoma is rare in adults, often leading to poor prognosis due to delayed diagnosis. This review aims to clarify its natural history and guide treatment strategies for adult patients.
Area of Science:
- Pediatric Oncology
- Urologic Oncology
Background:
- Embryonal rhabdomyosarcoma (ERMS) is a common pediatric prostate tumor.
- Adult ERMS is rare, with a generally poor prognosis compared to children.
Observation:
- This study presents two adult cases of prostate ERMS.
- Literature review focusing on the natural history and treatment of adult ERMS.
Findings:
- Adult ERMS presents unique challenges including lack of awareness, diagnostic delays, and aggressive tumor behavior.
- Combined modality treatment has improved outcomes in children, but adult prognosis remains poor.
Implications:
- Highlights the need for increased awareness of adult prostate ERMS.
- Aims to establish a definitive treatment policy for this rare adult malignancy.
Abstract:
Embryonal rhabdomyosarcoma of the prostate is a common tumour in infants and children. It is rarely seen in adults. The combined modality has improved outcome in children, where as in adults prognosis is poor. The lack of awareness of this entity in adults, delay in diagnosis and a more aggressive behavior of this malignancy are some of the reasons. We report two cases of embroyonal rhabdomyosarcoma of prostate in adults along with review of literature with an aim to define natural history and formulate treatment policy.
