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Published on: December 15, 2011
Wegener's granulomatosis diagnosed by testicular biopsy
Mahendra Agraharkar1, Sumita Gokhale, Rajiv Gupta
1Division of Nephrology, Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
Abstract:
Urogenital involvement, other than the kidneys, is extremely rare in Wegener's granulomatosis (WG) and occurs in less than 1% of the cases. When encountered it is confined to prostate, bladder, urethra, cervix, and vagina. Granulomatous infiltration of the testis from WG has not been cited in the medical literature. We report a case of WG in a Hispanic male who presented with sensorineural hearing loss and hemoptysis. He had a pulmonary lesion and a painless right testicular mass, which was found to have necrotizing granulomas on excisional biopsy. This may be the first reported case of WG diagnosed by testicular biopsy as testicular involvement is rare in WG. We believe that the actual incidence of testicular involvement in WG may be higher as genital examination may be ignored during routine physical examinations.