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Empirical, Metagenomic, and Computational Techniques Illuminate the Mechanisms by which Fungicides Compromise Bee Health
Published on: October 9, 2017
Antimicrobial compounds of fungi vectored by Clusia spp. (Clusiaceae) pollinating bees
Beatriz Bicalho1, Regina A C Gonçalves, Ana Paula M Zibordi
1Universidade Estadual de Campinas - UNICAMP, Instituto de Química, CP 6154, Campinas (SP) 13083-970, Brazil.
Abstract:
The production of antimicrobial compounds by fungi associated with Clusia spp. pollinating bees (Trigona sp., Trigonini) was investigated in order to approach natural mechanisms of microbial density control within nest environment. By using a bioassay-guided approach based on bioautography and minimal inhibitory concentration (MIC), known alpha,beta-dehydrocurvularin and curvularin were isolated from Curvularia eragrostidis (CCT 5634) and Curvularia pallescens (CCT 5654), and known cochlioquinone A and isocochlioquinone A were isolated from Drechslera dematioidea (CCT 5631).
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