Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Subcompartments of the endoplasmic reticulum.

B M Vertel1, L M Walters, D Mills

  • 1Department of Cell Biology and Anatomy, Chicago Medical School, IL 60064.

Seminars in Cell Biology
|October 1, 1992
PubMed
Summary

The endoplasmic reticulum (ER) is a complex organelle with specialized subcompartments. Its structure and function are dynamic, adapting to cellular needs and interactions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mapping Out Remediation: An Actionable Roadmap to Support Trainees Through Remediation.

Academic pediatrics·2024
Same author

Effects of silver diammine fluoride with/without potassium iodide on enamel and dentin carious lesions in primary teeth.

Frontiers in oral health·2024
Same author

Volumetric Response and Survival of Patients With Bulky IDH-Mutated Grade 3 Glioma Managed With FET-FDG-Guided Integrated Boost IMRT.

Clinical oncology (Royal College of Radiologists (Great Britain))·2024
Same author

Composite 3D printing of biomimetic human teeth.

Scientific reports·2022
Same author

The plate-to-rod transition in trabecular bone loss is elusive.

Royal Society open science·2021
Same author

IV treatment increase?

British dental journal·2021

Area of Science:

  • Cell Biology
  • Molecular Biology
  • Biochemistry

Background:

  • The endoplasmic reticulum (ER) is the largest endomembrane system in eukaryotic cells.
  • It exists as a network of interconnected tubules and flattened sacs, forming distinct subcompartments.
  • These subcompartments include the rough ER, nuclear envelope, and various smooth ER domains.

Purpose of the Study:

  • To review the structural and functional characteristics of ER subcompartments.
  • To explore the mechanisms underlying the formation and maintenance of ER domains.
  • To discuss the dynamic nature of the ER and its interactions with other cellular components.

Main Methods:

  • Literature review of existing research on endoplasmic reticulum structure and function.
  • Analysis of studies focusing on ER subcompartment formation, membrane associations, and functional specialization.
  • Examination of the dynamic properties of the ER, including assembly, disassembly, and inter-organelle exchange.

Main Results:

  • The ER comprises distinct subcompartments like the rough ER and nuclear envelope, each with specialized properties.
  • Formation of ER subcompartments is influenced by membrane associations and interactions with cytoplasmic and luminal factors.
  • ER subcompartments reflect specialized cellular functions and vary with the cell's physiological state.

Conclusions:

  • The endoplasmic reticulum is a highly organized and dynamic organelle with functionally specialized subcompartments.
  • These subcompartments are established and maintained through complex molecular interactions and membrane dynamics.
  • The ER's adaptability and inter-organelle exchange are crucial for cellular homeostasis and response to physiological changes.

Related Experiment Videos