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Related Experiment Videos

The effect of posterior capsule opacification on visual function.

William R Meacock1, David J Spalton, James Boyce

  • 1St. Thomas' Hospital, London, United Kingdom. wmeacock@hotmail.com

Investigative Ophthalmology & Visual Science
|October 28, 2003
PubMed
Summary

Posterior capsule opacification (PCO) significantly impacts visual function in pseudophakic eyes. Forward light scatter is the most sensitive indicator of PCO effects, preceding contrast sensitivity and visual acuity changes.

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Area of Science:

  • Ophthalmology
  • Visual Science

Background:

  • Pseudophakic eyes can develop posterior capsule opacification (PCO) after cataract surgery.
  • PCO can potentially impair visual function, necessitating investigation into its effects.

Purpose of the Study:

  • To quantify the impact of posterior capsule opacification (PCO) on various visual functions in pseudophakic eyes.
  • To determine the sensitivity of different visual tests to PCO.

Main Methods:

  • 106 eyes undergoing uncomplicated phacoemulsification were assessed.
  • Posterior capsule opacification (PCO) was quantified using digital retroillumination imaging.
  • Visual function was evaluated through high- and low-contrast visual acuity (ETDRS charts), contrast sensitivity (Pelli-Robson, CSV-1000), and forward light scatter.

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Main Results:

  • A PCO percentage of 78% was required to reduce high-contrast visual acuity.
  • Low-contrast acuity and Pelli-Robson contrast sensitivity declined with 46% PCO.
  • CSV-1000 contrast sensitivity decreased with 38-51% PCO, while forward light scatter was affected by less than 1% PCO.

Conclusions:

  • Central PCO affects psychophysical test results with varying sensitivity.
  • Forward light scatter is the most sensitive measure of PCO's impact on vision.
  • Contrast sensitivity and visual acuity are affected by higher degrees of PCO.