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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
Echocardiographic assessment of right ventricular obstruction in hypertrophic cardiomyopathy
Masatoshi Shimizu1, Hiroya Kawai, Yoshiyuki Yokota
1Division of Cardiovascular and Respiratory Medicine, Kobe University Graduate School of Medicine, Japan. simizum@nkh.hosp.go.jp
Insights
Echocardiography identified right ventricular obstruction in 14% of hypertrophic cardiomyopathy patients, often co-occurring with left ventricular obstruction. This imaging technique effectively evaluated obstruction sites and characteristics.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Hypertrophic cardiomyopathy (HCM) is a genetic heart disease characterized by abnormal thickening of the heart muscle.
- Right ventricular (RV) involvement in HCM, though less studied than left ventricular (LV) issues, can significantly impact patient outcomes.
- Understanding the prevalence and characteristics of RV obstruction is crucial for comprehensive HCM management.
Purpose of the Study:
- To evaluate the incidence, flow dynamics, and morphological features of RV obstruction in patients with HCM.
- To determine the correlation between RV obstruction and LV obstruction in this patient cohort.
- To assess the utility of echocardiography in identifying and characterizing RV obstruction in HCM.
Main Methods:
- Utilized echocardiography, including color flow mapping and continuous wave Doppler, in 91 patients with HCM.
- Measured ventricular wall thickness to assess hypertrophy extent.
- Defined obstruction based on flow velocity (<2.0 m/s) and Doppler waveform characteristics.
Main Results:
- Right ventricular obstruction was identified in 14 patients (15.4%).
- Six of these patients (43%) also exhibited left ventricular obstruction.
- RV obstructions were located in the outflow tract (9), mid-base septal bulge (2), and apical trabecular region (3).
- Doppler flow patterns varied, with some persisting into early diastole.
Conclusions:
- Echocardiography is a valuable tool for evaluating RV obstruction in HCM.
- RV obstruction is a significant finding in HCM patients, frequently associated with LV obstruction.
- Morphological characteristics and flow dynamics of RV obstruction can be effectively assessed using echocardiography.
Abstract:
Echocardiography was used to evaluate the incidence, flow dynamics and morphological characteristics of right ventricular obstruction in 91 patients with hypertrophic cardiomyopathy. Color flow mapping was used to define the sites of obstruction in the left and right ventricles. Ventricular obstruction was considered to be present if the flow velocity was less than 2.0 m/s as measured by continuous wave Doppler. The thickness of both the right ventricular free wall and anterior ventricular septum was measured to assess the magnitude and extent of hypertrophy. Right ventricular obstruction was present in 14 patients of whom 6 (43%) had left ventricular obstruction also. The right ventricular obstructions were found in the outflow tract (9 patients), mid-base septal bulge (2 patients) and apical trabecular region (3 patients). Doppler waveform was confined to systole in all patients with obstruction in the outflow tract and in one of the patients with mid-base septal bulge. Moreover, the flow wave persisted into early diastole in 4 patients, including 2 with apical trabecular obstruction. The thickness of both the right ventricular free wall and anterior ventricular septum suggested that these hypertrophied regions were the sites of right ventricular obstruction. Thus, echocardiography was useful in evaluating right ventricular obstruction in hypertrophic cardiomyopathy.
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