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Updated: Aug 30, 2026

Ex Vivo Perfusion of the Rodent Placenta
Published on: May 30, 2019
Uterine perforation following manual removal of the placenta
Sayaka Okudaira1, Toyohiko Kuwashima, Nobuya Mine
1Department of Obstetrics and Gynecology, Tokyo Rinkai Hospital, Japan.
We present here a case of uterine perforation following manual removal of the placenta during the third stage of normal labor. Total abdominal hysterectomy was performed, and the 4x3-cm perforation of the uterus and placenta accreta were confirmed. In this case, the round ligament covering the hematoma prevented bleeding into the peritoneal cavity and peritonitis. Manual removal of the placenta should be performed carefully following ultrasonographic assessment for placental abnormalities such as placenta accreta.
We present here a case of uterine perforation following manual removal of the placenta during the third stage of normal labor. Total abdominal hysterectomy was performed, and the 4x3-cm perforation of the uterus and placenta accreta were confirmed. In this case, the round ligament covering the hematoma prevented bleeding into the peritoneal cavity and peritonitis. Manual removal of the placenta should be performed carefully following ultrasonographic assessment for placental abnormalities such as placenta accreta.
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