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Related Experiment Videos

Non-pulsatile circulatory support in 90 cases.

C H Moore1, J W Dailey, D S Canon

  • 1Humana Heart Institute, San Antonio, Texas.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|July 1, 1992
PubMed
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Non-pulsatile circulatory support significantly improves survival rates for critically ill cardiac patients. Early implementation and careful patient selection are key to achieving better outcomes in complex cardiovascular procedures.

Area of Science:

  • Cardiovascular Surgery
  • Critical Care Medicine
  • Biomedical Engineering

Background:

  • Low survival rates (<10% cardiac arrest, <50% cardiogenic shock, 11-21% post-cardiotomy failure to wean) highlight critical unmet needs.
  • Existing circulatory support methods have shown limited efficacy in severe cardiac conditions.

Purpose of the Study:

  • To evaluate the impact of non-pulsatile circulatory support on survival rates in patients undergoing major cardiovascular procedures.
  • To assess the effectiveness of the emergent cardiopulmonary bypass system (CPS) and the BioMedicus centrifugal pump (VAD) in improving patient outcomes.

Main Methods:

  • Retrospective analysis of 90 consecutive cases utilizing non-pulsatile circulatory support from 1986-1991.
  • Implementation of an emergent cardiopulmonary bypass system (CPS) in 67 patients.

Related Experiment Videos

  • Use of the BioMedicus centrifugal pump (VAD) for post-cardiotomy failure to wean and as a bridge to transplant.

    • Main Results:

    • Overall survival >30 days was 31% (21/67) for patients receiving CPS, with 51% weaned or transferred.
    • For patients receiving the VAD, 48% (11/14) survived >30 days.
    • A combined survival of 37% is achievable for patients who might not otherwise survive with careful selection and early support implementation.

    Conclusions:

    • Non-pulsatile circulatory support, including CPS and VADs, offers a viable strategy to improve survival in high-risk cardiovascular patients.
    • Early implementation and a multidisciplinary team approach (surgeons, perfusionists, nurses) are crucial for successful outcomes.
    • These devices are cost-effective and widely available, making them a valuable option for many hospitals.