Determination of cholesterol using o-phthalaldehyde

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Updated: Aug 30, 2026

Cholesterol Efflux Assay
07:54

Cholesterol Efflux Assay

Published on: March 6, 2012

L L Rudel1, M D Morris

  • 1Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada, and Departments of Biochemistry and Pediatrics, University of Arkansas Medical Center, Little Rock, Arkansas 72201.

Journal of Lipid Research
|May 1, 1973
PubMed

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Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...