Related Experiment Video
Updated: Aug 30, 2026
Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
Correlations between preprocedure mood and clinical outcome in patients undergoing coronary angioplasty
Gregory E Grunberg1, Suzanne W Crater, Cynthia L Green
1Division of Cardiology, Department of Medicine, Durham Veterans Administration Medical Center and the Duke Clinical Research Institute, Durham, North Carolina, USA.
Insights
Pre-procedure hope and happiness scores correlate with better outcomes after percutaneous coronary intervention (PCI). Higher hope before PCI linked to lower ischemic burden, while improved mood predicted survival.
Area of Science:
- Cardiology
- Psychology
- Medical Psychology
Background:
- Percutaneous coronary intervention (PCI) is a common procedure for coronary artery disease.
- Patient mood states before PCI may influence procedural outcomes and long-term prognosis.
- Understanding the relationship between pre-procedural mood and clinical endpoints is crucial for patient care.
Purpose of the Study:
- To investigate the association between pre-procedural mood and clinical outcomes following PCI.
- To examine the correlation between mood shifts during interventions (stress relaxation, imagery, prayer) and procedural success.
- To assess the predictive value of mood states on adverse cardiac events and 6-month mortality.
Main Methods:
- A cohort of 119 patients with unstable angina or myocardial infarction undergoing PCI was studied.
- Patients completed a Visual Analog Scale (VAS) assessing various mood states (hope, happiness, worry, etc.) before and after interventions.
- Interventions included stress relaxation, imagery, touch, prayer, or standard care, with mood assessed approximately 30 minutes apart.
Main Results:
- A higher hope score before PCI was significantly correlated with a lower total ischemic burden during the procedure.
- Patients experiencing adverse cardiac events (ACE) post-PCI had significantly lower pre-procedural hope and happiness scores.
- Survivors at 6 months demonstrated significantly greater increases in hope and worry scores compared to non-survivors.
Conclusions:
- Simple mood assessments prior to PCI show correlations with clinical outcomes during and after the procedure.
- Pre-procedural hope and happiness appear to be important indicators of procedural success and patient prognosis.
- Further research is warranted to explore whether mood-altering interventions can positively impact clinical outcomes in PCI patients.
Abstract:
We studied the relationship between mood and mood shift immediately before percutaneous coronary intervention (PCI) and 3 end points: total ischemic burden during PCI, adverse cardiac end points (ACE) after PCI, and death by 6-month follow up. Patients (n = 119) with unstable angina or myocardial infarction completed a visual analog scale (VAS) twice before PCI; before and after a session of stress relaxation, imagery, or touch; or approximately 30 minutes apart for patients assigned to prayer or to standard care. VAS included happiness, satisfaction, calm, hope, worry, shortness of breath, fear, and sadness. We observed a significant correlation between higher hope score before PCI and lower ischemic burden. Patients who experienced ACE had significantly lower hope and happiness scores than those who did not. Patients who survived to 6 months had significantly greater increases in worry and in hope. Our data suggest correlations between simple mood assessments before PCI and clinical outcomes during and after the procedure. More study is needed to understand whether attempts to alter patient mood can affect clinical outcomes.
Related Concept Videos
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:27Coronary Artery Disease V: Interprofessional Care
01:28Cardiomyopathy VII: Pre and Post Operative Nursing Management
01:30Coronary Artery Disease III: Clinical Manifestations