Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glucose and mannitol diffusion in human dura mater.

Alexey N Bashkatov1, Elina A Genina, Yuri P Sinichkin

  • 1Department of Optics, Saratov State University, Saratov, Russia. bash@optics.sgu.ru

Biophysical Journal
|October 29, 2003
PubMed
Summary

Researchers controlled human dura mater optical properties using glucose and mannitol solutions. This study demonstrates increased tissue transparency and light penetration, crucial for optical applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Computational and experimental investigation of nanoparticle effects on tissue optical properties and optical coherence tomography imaging.

Biomedical optics express·2026
Same author

Spectral Studies of a Novel Photosensitizer Complex for Photodynamic Therapy.

Current pharmaceutical biotechnology·2026
Same author

Metal-Enhanced Fluorescence of Nanocomplexes.

Materials (Basel, Switzerland)·2026
Same author

Optical Coherence Tomography Mapping of the Scattering Coefficient to Study the Skin Hydration Process under Optical Clearing.

Skin pharmacology and physiology·2026
Same author

Biophysical Alterations of the Stratum Corneum Induced by Optical Clearing Agents: Implications for Efficiency and Safety Optimization.

Skin pharmacology and physiology·2026
Same author

Next-generation biomedical sensing through photoacoustic-electrochemical synergy.

Medical review (2021)·2026

Area of Science:

  • Biomedical Engineering
  • Ophthalmology
  • Tissue Optics

Background:

  • The optical properties of the human dura mater are critical for various biomedical applications, including surgical visualization and light-based therapies.
  • Understanding how to modulate these properties is essential for improving outcomes in procedures involving the dura mater.

Purpose of the Study:

  • To investigate the effect of aqueous glucose and mannitol solutions on the optical properties of human dura mater in vitro.
  • To determine the diffusion coefficients of glucose and mannitol within the dura mater tissue.
  • To assess the potential for controlling dura mater transparency for enhanced light penetration.

Main Methods:

  • In vitro experimental setup using human dura mater tissue samples.
  • Administration of aqueous solutions of glucose and mannitol.

Related Experiment Videos

  • Measurement of optical transmittance changes.
  • Estimation of diffusion coefficients using established methods.

    • Main Results:

    • A significant increase in the optical transmittance of the dura mater was observed upon administration of immersion liquids.
    • The diffusion coefficients for glucose and mannitol in human dura mater at 20°C were estimated as (1.63 ± 0.29) x 10⁻⁶ cm²/s and (1.31 ± 0.41) x 10⁻⁶ cm²/s, respectively.
    • Effective control over dura mater optical characteristics was achieved, leading to increased transparency.

    Conclusions:

    • Aqueous solutions of glucose and mannitol can effectively alter the optical properties of the human dura mater.
    • The observed increase in transparency enhances light penetration through the tissue.
    • These findings suggest potential applications in improving optical access for diagnostic and therapeutic interventions involving the dura mater.