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Updated: Jul 1, 2026

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface
Published on: February 23, 2020
[Definition of acceptable operator exposure levels (AOELs) to pesticides]
1International Centre for Pesticides and Health Risk Prevention (ICPS), Ospedale Luigi Sacco (MI), Dipartimento di Medicina occupazionale e Ambientale dell'Università degli Studi di Milano.
Abstract:
A guidance document entitled "Recommended method for the establishment of Acceptable Operator Exposure Levels" has been prepared within the EU 5th Framework program. The paper describes the main outcomes of the project and the issues that apply particularly to agricultural workers and bystanders and the difficulties in developing an agreed uniform approach. The scientific basis of the process is discussed, to be used by the European Commission and Member States when making decision about the inclusion of an active substance in Annex 1 of Directive 91/414/EEC.
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