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Postmenopausal screening for osteopenia.

P J Ryan1, G M Blake, I Fogelman

  • 1Department of Nuclear Medicine, Guy's Hospital, London.

British Journal of Rheumatology
|December 1, 1992
PubMed
Summary
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Dual energy X-ray absorptiometry (DXA) screening for osteopenia in women aged 40-60 reveals bone mineral density (BMD) is not reliably predicted by lifestyle factors. Both spine and hip BMD should be considered for accurate assessment.

Area of Science:

  • Osteoporosis and Bone Metabolism
  • Diagnostic Imaging in Women's Health

Background:

  • Osteopenia screening is crucial for identifying women at risk of bone loss.
  • Dual energy X-ray absorptiometry (DXA) is a standard method for measuring bone mineral density (BMD).

Purpose of the Study:

  • To evaluate the predictive value of lifestyle factors and identify reliable thresholds for osteopenia diagnosis.
  • To assess the correlation between lumbar spine and femoral neck BMD in women aged 40-60.

Main Methods:

  • DXA scans of the lumbar spine and femoral neck were performed on 627 women aged 40-60.
  • Detailed medical histories including lifestyle parameters and risk factors were collected.
  • Statistical analysis was used to determine correlations between BMD and various factors.

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Main Results:

  • Mean lumbar spine BMD was 0.946 g/cm², and mean femoral neck BMD was 0.767 g/cm².
  • Weight and years post-menopause showed weak correlations with BMD (r = 0.20-0.24).
  • Correlation between spinal and femoral neck BMD was moderate (r = 0.64), indicating the need for dual-site assessment.

Conclusions:

  • Lifestyle factors and weight are not sufficiently reliable predictors of BMD for clinical use.
  • Both lumbar spine and femoral neck BMD measurements are necessary for comprehensive individual assessment.
  • The study provides BMD percentiles to aid in defining treatment thresholds for osteopenia.