Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Effects of kelp supplementation on thyroid function in euthyroid subjects.

Clifford D Clark1, Bertram Bassett, Mark R Burge

  • 1Department of Internal Medicine, Division of Endocrinology and Metabolism, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|October 30, 2003
PubMed
Summary

Supplemental kelp significantly increases thyroid-stimulating hormone (TSH) levels in healthy adults. Further research is needed to assess long-term effects of kelp on thyroid health.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A patient-centered comparative effectiveness research study of culturally appropriate options for diabetes self-management.

medRxiv : the preprint server for health sciences·2023
Same author

Association Between Patient Factors and the Effectiveness of Wearable Trackers at Increasing the Number of Steps per Day Among Adults With Cardiometabolic Conditions: Meta-analysis of Individual Patient Data From Randomized Controlled Trials.

Journal of medical Internet research·2022
Same author

Evidence-based practice strategies for faculty professional development in clinical translational research at Institutional Development Award (IDeA) state institutions in the Mountain West.

Journal of clinical and translational science·2022
Same author

The associations between COVID-19 diagnosis, type 1 diabetes, and the risk of diabetic ketoacidosis: A nationwide cohort from the US using the Cerner Real-World Data.

PloS one·2022
Same author

Preoperative vitamin D deficiency is associated with increased risk of postoperative hypocalcemia after total thyroidectomy.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research·2021
Same author

AMPK is activated during lysosomal damage via a galectin-ubiquitin signal transduction system.

Autophagy·2020

Area of Science:

  • Endocrinology
  • Nutritional Science

Background:

  • Thyroid function is crucial for metabolism and overall health.
  • Kelp is a rich source of iodine, a key component of thyroid hormones.
  • Understanding the impact of kelp supplementation on thyroid function is important for public health.

Purpose of the Study:

  • To investigate the effects of two different doses of supplemental kelp on thyroid function in healthy individuals.
  • To assess changes in thyrotropin (TSH), free thyroxine, and total triiodothyronine levels.
  • To evaluate the impact on TSH response to thyrotropin-releasing hormone stimulation and urinary iodine excretion.

Main Methods:

  • A double-blind, placebo-controlled clinical trial was conducted with 36 healthy euthyroid subjects.
  • Participants were randomized to receive placebo, low-dose kelp, or high-dose kelp for 4 weeks.

Related Experiment Videos

  • Thyroid function tests, urinary iodine excretion, and basal metabolic rate were measured at baseline and after 4 weeks.

    • Main Results:

    • Kelp supplementation significantly increased both basal and poststimulation TSH levels in a dose-dependent manner.
    • Free thyroxine levels remained unchanged, while total triiodothyronine decreased with high-dose kelp.
    • Urinary iodine excretion increased with kelp intake, but basal metabolic rate did not change significantly.

    Conclusions:

    • Short-term kelp supplementation can significantly alter thyroid function markers, primarily by increasing TSH.
    • These effects are comparable to those observed with supplemental iodine in euthyroid subjects.
    • Long-term consequences of kelp supplementation on thyroid health require further investigation.