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Related Experiment Videos

Family intervention for schizophrenia.

F M Pharoah1, J Rathbone, J J Mari

  • 1Willow House, Littlemore Mental Health Centre, Sandford Rd, Oxford, UK, OX4 4XN. fiona.pharaoh@oxmhc-tr.nhs.uk

The Cochrane Database of Systematic Reviews
|October 30, 2003
PubMed
Summary

Family psychosocial interventions may reduce relapse rates and improve medication adherence for individuals with schizophrenia. However, current evidence is statistically heterogeneous, necessitating further research for definitive conclusions.

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Public Health

Background:

  • High expressed emotion in families is linked to increased relapse rates in schizophrenia.
  • Psychosocial interventions aim to reduce family stress and relapse rates.
  • These interventions are supplementary to, not replacements for, pharmacotherapy.

Purpose of the Study:

  • To evaluate the effectiveness of community-based family psychosocial interventions for schizophrenia care.
  • To compare these interventions against standard care.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials (RCTs) and quasi-RCTs.
  • Searches included major databases up to November 2002.
  • Included studies compared family-based psychosocial interventions (≥5 sessions) with standard care for schizophrenia or schizoaffective disorder.

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Main Results:

  • Family interventions showed a potential to decrease relapse frequency (RR 0.72, NNT 7) and improve medication compliance (RR 0.74, NNT 7).
  • Data exhibited statistical heterogeneity, with a trend towards the null effect.
  • No significant impact on dropout rates was observed; improvements in social functioning and reduced expressed emotion were noted.

Conclusions:

  • The current evidence base does not provide high confidence in the effects of family interventions.
  • Further data from completed trials are needed to inform clinical practice.
  • Additional trials are warranted if aligned with routine care parameters.