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A t(2;3)(q12-13;p24-25) in follicular thyroid adenomas
G Sozzi1, M Miozzo, T C Cariani
1Division of Experimental Oncology A, Istituto Nazionale Tumori, Milan, Italy.
Cancer Genetics and Cytogenetics
|November 1, 1992
Abstract:
We report the cytogenetic analysis of five cases of follicular thyroid adenoma. In two of them, we observed an identical t(2;3)(q12-13;p24-25) as a unique chromosome change. A third case showed a hyperdiploid karyotype with trisomies of chromosomes 7 and 12. Two cases had a normal diploid karyotype. These changes could define subgroups of follicular adenomas endowed with different malignant potential.