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Pseudomyxoma peritonei, origin from appendix: report of cases with images

Chung-Wah Lam1, Shou-Jen Kuo, Hung-Chi Chang

  • 1Department of General Surgery, Changhua Christian Hospital, Changhua, Taiwan, ROC. 91662@cch.org.tw

International Surgery
|October 31, 2003
PubMed

Insights

Pseudomyxoma peritonei is a rare condition often found incidentally during surgery. Current management involves surgical excision and chemotherapy, with survival rates varying by disease type.

Area of Science:

  • Oncology
  • Gastroenterology
  • Surgical Pathology

Background:

  • Pseudomyxoma peritonei (PMP) is an uncommon neoplasm characterized by mucinous ascites.
  • Etiology is often linked to appendiceal or ovarian tumors.

Observation:

  • Presents three cases of PMP discovered incidentally during surgical procedures in adult women.
  • Patients' ages ranged from 47 to 80 years.

Findings:

  • No universally effective treatment exists for PMP.
  • Current therapeutic strategies combine radical surgical excision (including appendicectomy and oophorectomy in women) with hyperthermic intraperitoneal and systemic chemotherapy.
  • Bowel and biliary obstruction are significant causes of morbidity and mortality.

Implications:

  • The 5-year survival rate for PMP ranges from 53-75%, contingent on malignancy.
  • Median survival under surgical management is approximately 2 years.
  • Further research into novel therapeutic approaches for PMP is warranted.

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