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Breast conservation in patients with multiple ipsilateral synchronous cancers
Jess Kaplan1, Gladys Giron, Paul Ian Tartter
1Department of Surgery, St Luke's-Roosevelt Hospital Center, New York, NY, USA.
Journal of the American College of Surgeons
|October 31, 2003
Summary
Breast conservation surgery is an effective treatment for multiple synchronous ipsilateral breast cancers, offering comparable survival rates to mastectomy. This approach allows more patients to preserve their breast while achieving similar disease-free survival outcomes.
Area of Science:
- Oncology
- Surgical Oncology
- Breast Cancer Research
Background:
- Breast conservation therapy (BCT) survival is comparable to mastectomy.
- Contraindications for mastectomy are being re-evaluated.
- Focus on BCT for multiple synchronous ipsilateral breast cancers.
Purpose of the Study:
- Compare outcomes of BCT versus mastectomy for multiple ipsilateral breast cancers.
- Evaluate disease-free survival and local recurrence rates.
- Assess patient characteristics and treatment differences.
Main Methods:
- Prospective database review of patients (1989-2002).
- Comparison of 36 BCT patients with 19 mastectomy patients.
- Analysis of demographics, cancer pathology, and survival data.
Main Results:
- No significant differences in patient/tumor characteristics between BCT and mastectomy groups.
- BCT patients more likely to need re-excision and receive radiotherapy.
- Comparable 5-year disease-free survival (97% BCT vs. 100% mastectomy) and distant metastasis rates (3% vs. 5%).
Conclusions:
- Breast conservation is a viable and effective treatment option for multiple synchronous ipsilateral breast cancers.
- Achieves comparable oncologic outcomes to mastectomy.
- Supports BCT as a standard treatment for selected patients.