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Related Experiment Videos

Rickets.

Brian Wharton1, Nick Bishop

  • 1MRC Childhood Nutrition Research Centre, Institute of Child Health, WC1N 1EH, London, UK. bwharton@ich.ucl.ac.uk

Lancet (London, England)
|October 31, 2003
PubMed
Summary
This summary is machine-generated.

Rickets is reappearing globally, primarily due to vitamin D deficiency. Factors like exclusive breastfeeding without supplementation and reduced sun exposure contribute to this growing public health concern.

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Area of Science:

  • Nutritional Science
  • Pediatrics
  • Public Health

Background:

  • Rickets, a disease historically considered controlled, is experiencing a resurgence worldwide.
  • While present in less developed nations, it's also a growing concern in temperate regions, particularly among immigrant populations.

Purpose of the Study:

  • To review the multifaceted factors influencing the clinical presentation of rickets.
  • To focus on nutrient deficiency as the primary cause, specifically vitamin D deficiency.
  • To explore the reasons behind the increased prevalence of rickets in specific demographics and regions.

Main Methods:

  • Review of existing literature and epidemiological data on rickets.
  • Analysis of genetic, developmental, and environmental influences on rickets.

Related Experiment Videos

  • Investigation of nutrient deficiencies, particularly vitamin D, calcium, and iron.

    • Main Results:

    • Vitamin D deficiency is identified as the predominant cause of nutritional rickets.
    • Exclusive breastfeeding without vitamin D supplementation and reduced skin production of vitamin D are significant contributing factors.
    • High prevalence of rickets in immigrant children in temperate climates suggests complex underlying causes, possibly including genetic, environmental, and nutritional interactions.

    Conclusions:

    • Re-emphasizing dietary vitamin D supplementation for children and pregnant women is crucial.
    • Further research is needed to understand the specific reasons for vitamin D deficiency in immigrant populations, with iron deficiency being a potential factor.
    • Public health strategies must address the resurgence of rickets through targeted supplementation and awareness campaigns.