Cough . 2: Chronic cough in children

J C de Jongste1, M D Shields

  • 1Department of Pediatric Respiratory Medicine, Sophia Children's Hospital/Erasmus MC University Medical Center, Rotterdam, The Netherlands. j.c.dejongste@erasmusmc.nl

Thorax
|October 31, 2003
PubMed

Insights

Chronic cough in children often stems from viral infections. Persistent or severe coughs, especially with poor growth, warrant excluding serious conditions like cystic fibrosis or congenital issues.

Area of Science:

  • Pediatrics
  • Respiratory Medicine

Background:

  • Chronic cough is a frequent pediatric concern.
  • Viral infections are the primary cause in children.
  • Underlying conditions must be considered for severe or persistent coughs.

Purpose of the Study:

  • To highlight the differential diagnosis of chronic cough in children.
  • To emphasize the importance of early diagnosis for specific pediatric respiratory conditions.

Main Methods:

  • Review of common and rare causes of chronic cough in pediatric populations.
  • Emphasis on clinical indicators for further investigation.

Main Results:

  • Viral infections are the most common cause of chronic cough.
  • Passive smoking is a significant contributing factor.
  • Specific diagnoses like cystic fibrosis, foreign body aspiration, congenital abnormalities, and primary ciliary dyskinesia require exclusion.

Conclusions:

  • Early identification of underlying diseases is crucial, particularly in younger children.
  • Chronic productive cough with purulent sputum is a serious sign, not typical of asthma.
  • A thorough diagnostic approach is necessary for effective management of pediatric chronic cough.

Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations01:19

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...