Related Experiment Video
Updated: Aug 30, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
[Loss of visual acuity due to choroidal ischemia in Fabry's disease]
J-M Guenoun1, C Parc, D Monnet
1Service d'ophtalmologie, Hôpital Cochin, 27, rue du Faubourg Saint-Jacques, 75679 Paris 14.
Abstract:
We report a case of a 21-year-old man with Fabry's disease who presented with a sudden decrease in visual acuity to 20/200 in the left eye. Pale areas with a lobular choroidal distribution were seen on fundus examination. No retinal vascular causes were found on further evaluation. With anticoagulation treatment, the patient's subsequent course was good, with visual recovery to 20/25 and normalization of the funduscopic appearance. Recovery of both visual acuity and the pale, lobular areas suggested a choroidal etiology, probably ischemic because of the sudden onset. Choroidian ischemia is therefore a cause of visual acuity loss in Fabry's disease, so far not described in the literature.
Related Concept Videos
Photoreceptors and Visual Pathways
Diabetic Retinopathy
Glaucoma: Overview
Focusing of Light in the Eye
