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Updated: Aug 30, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
A large unilateral renal artery aneurysm in a young child
Pierre Robitaille1, Hélène Lord, Josée Dubois
1Department of Pediatrics, Nephrology Division, Hospital Ste-Justine, 3175 Chemin Cote Sainte-Catherine, Montreal, Québec, H3T1C5, Canada. probitaillemd@hotmail.com
Abstract:
The case of a 13-month-old boy with fibromuscular dysplasia (FMD) presenting with a large saccular aneurysm of the left renal artery and renovascular hypertension is reported. Renal and intrarenal arteries showed numerous small aneurysms alternating with stenoses. All arterial lesions were localized to the left kidney. After left nephrectomy, the patient's blood pressure normalized. Histopathologic examination of the arteries disclosed changes typical of medial fibroplasias, the most frequently described form of FMD in children. This diagnosis is rewarding as it represents a surgically curable cause of severe hypertension.
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