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Updated: Aug 30, 2026

Lipid-Protein Membrane Structure-Function Characterization using Droplet Interface Bilayers
Published on: June 12, 2026
Biphasic constitutive laws for biological interface evolution
P Büchler1, D P Pioletti, L R Rakotomanana
1LRO, Bat. AAB, Laboratory of Orthopedic Research, EPFL, 1015 Lausanne, Switzerland. philippe.buechler@epfl.ch
Abstract:
A model of tissue differentiation at the bone-implant interface is proposed. The basic hypothesis of the model is that the mechanical environment determines the tissue differentiation. The stimulus chosen is related to the bone-implant micromotions. Equations governing the evolution of the interfacial tissue are proposed and combined with a finite element code to determine the evolution of the fibrous tissue around prostheses. The model is applied to the case of an idealized hip prosthesis.
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