Related Experiment Video
Updated: Aug 12, 2026

Cholesterol Efflux Assay
Published on: March 6, 2012
When do we treat hypercholesterolemia?
1Department of Medicine, Emory University, Atlanta, Georgia 30322.
Insights
Clinicians face challenges in treating high cholesterol despite established guidelines. Patient-specific factors and risk assessment are crucial for effective hypercholesterolemia management and coronary heart disease prevention.
Area of Science:
- Cardiology
- Public Health
Background:
- Established link between elevated total and low-density lipoprotein (LDL) cholesterol and coronary heart disease (CHD).
- Availability of published treatment guidelines for hypercholesterolemia.
Observation:
- Clinicians encounter complex issues in determining patient eligibility for treatment.
- Specific patient characteristics and risk factors influence treatment decisions, but less is understood about them.
Findings:
- Review of current hypercholesterolemia treatment guidelines.
- Identification of therapeutic issues critical for patient selection.
Implications:
- Need for personalized treatment approaches considering individual patient profiles.
- Enhanced understanding of risk factors can optimize hypercholesterolemia management strategies.
Abstract:
Although the relationships between elevated total and low-density lipoprotein (LDL) cholesterol and coronary heart disease (CHD) are relatively well established and published treatment guidelines are available, clinicians face a number of complex issues when deciding whom to treat. Specific patient characteristics and potential risk factors, of which less is known, may influence treatment decisions. In this presentation, the current guidelines for treating patients with hypercholesterolemia are reviewed and therapeutic issues that must be considered when selecting patients for treatment are identified.
Related Concept Videos
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Lipids: Dietary Sources and Requirements
Cholesterol: Significance and Regulation
Considering cholesterol and...
Coronary Artery Disease IV: Preventive Measures
Angina IV: Management
Atherosclerosis III: Management

