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Updated: Aug 30, 2026

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Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography
Johannes F de Boer1, Barry Cense, B Hyle Park
1Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom Street, BAR 724, Boston, Massachusetts 02114, USA. deboer@helix.mgh.harvard.edu
Optics Letters
|November 1, 2003
Abstract:
A signal-to-noise ratio (SNR) analysis is presented for optical coherence tomography (OCT) signals in which time-domain performance is compared with that of the spectral domain. A significant SNR gain of several hundredfold is found for acquisition in the spectral domain. The SNR benefit is demonstrated experimentally in a hybrid time-domain-spectral-domain OCT system.

