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TWINAN90: a FORTRAN program for conducting ANOVA-based and likelihood-based analyses of twin data
C J Williams1, J C Christian, J A Norton
1Department of Medical Genetics, Indiana University School of Medicine, Indianapolis.
Computer Methods and Programs in Biomedicine
|July 11, 1992
Summary
TWINAN90 is a versatile program for twin data analysis, integrating ANOVA-based methods and maximum likelihood estimation. It aids preliminary analyses and generates compatible files for advanced quantitative genetics software.
Area of Science:
- Quantitative Genetics
- Biometrical Genetics
- Statistical Genetics
Background:
- Twin studies are crucial for dissecting genetic and environmental influences on traits.
- Existing twin analysis programs may lack comprehensive features or integration.
- Sophisticated modeling requires specialized software and data formats.
Purpose of the Study:
- Introduce TWINAN90, a comprehensive software for twin data analysis.
- Highlight its capabilities in integrating ANOVA and path modeling.
- Demonstrate its utility as a preliminary analysis tool.
Main Methods:
- Incorporates ANOVA-based twin analyses from the TWINAN program.
- Features maximum likelihood estimation for three path models.
- Offers optional pedigree file output compatible with FISHER.
Main Results:
- TWINAN90 provides diverse analytical options for twin data.
- The program facilitates integration with other quantitative genetics packages like FISHER.
- Diagnostic features enhance its utility for preliminary analyses.
Conclusions:
- TWINAN90 is a valuable tool for researchers in quantitative and biometrical genetics.
- Its integrated approach and compatibility streamline complex twin data analyses.
- The program supports a range of analyses from preliminary to advanced modeling.