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Updated: Aug 30, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
Traditional and computerized assessment procedures applied to the evaluation of memory change after temporal
R J Ivnik1, J F Malec, F W Sharbrough
1Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA.
Abstract:
After establishing that 40 temporal lobectomy patients (20 right, 20 left) demonstrated the same pattern of memory compromise as has been reported in prior studies, we examined the sensitivity of computerized tests of everyday memory skills to the cognitive change associated with temporal resection. Multiple cognitive deficits occur after left, but not after right, temporal lobectomies. Memory impairment after surgery is not limited to traditionally structured memory tests but is also evident on tasks designed to simulate activities of daily life.
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