Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Patterns of memory dysfunction among children surviving temporal lobe tumors.

S C Carpentieri1, R K Mulhern

  • 1St. Jude's Children's Research Hospital, Division of Psychology, Department of Pediatrics, University of Tennessee College of Medicine, Memphis, 38101-0318, USA.

Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists
|July 1, 1993
PubMed
Summary

Children with temporal lobe tumors face memory and academic challenges. Radiation therapy increases the risk of verbal memory issues, impacting reading and spelling skills.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ectasia of the basilar artery in children with sickle cell disease: relationship to hematocrit and psychometric measures.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2007
Same author

Neuropsychological resiliency after treatment for advanced stage neuroblastoma.

Bone marrow transplantation·2005
Same author

Memory deficits among children with craniopharyngiomas.

Neurosurgery·2002
Same author

Excellent therapeutic efficacy and minimal late neurotoxicity in children treated with 18 grays of cranial radiation therapy for high-risk acute lymphoblastic leukemia: a 7-year follow-up study of the Dana-Farber Cancer Institute Consortium Protocol 87-01.

Cancer·2001
Same author

Who can decide what is in a child's best interest? A problem-solving approach.

Medical and pediatric oncology·2001
Same author

Patterns of intellectual development among survivors of pediatric medulloblastoma: a longitudinal analysis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2001

Area of Science:

  • Neuroscience
  • Pediatric Oncology
  • Cognitive Psychology

Background:

  • Temporal lobe tumors can affect cognitive functions in children.
  • Long-term neurocognitive outcomes after treatment are not fully understood.

Purpose of the Study:

  • To compare cognitive functioning in children with left versus right temporal lobe tumors.
  • To identify risk factors for cognitive deficits, particularly memory dysfunction, post-treatment.

Main Methods:

  • Cognitive assessment of 14 children (7 left, 7 right temporal lobe tumors) post-intervention (surgery + radiation).
  • Analysis of IQ, memory, and academic achievement, adjusting for general intelligence.

Main Results:

  • No significant differences in general IQ or specific cognitive factors between left and right tumor groups.

Related Experiment Videos

  • Auditory-verbal and visual-verbal memory dysfunction identified in a subset of children.
  • Radiation therapy was linked to a higher risk of verbal memory problems.
  • Reading and spelling achievement correlated with verbal memory performance.

    • Conclusions:

    • Children with temporal lobe tumors are at increased risk for memory dysfunction and academic difficulties.
    • Radiation therapy is a significant risk factor for verbal memory impairment.
    • Hemispheric lateralization of the tumor may not consistently predict specific cognitive deficits.