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Updated: Aug 30, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Polysomnographic study of sleeplessness and oneiricisms in the alcohol withdrawal syndrome
Giuseppe Plazzi1, Pasquale Montagna, Stefano Meletti
1Institute of Clinical Neurology, University of Bologna, via Ugo Foscolo 7, 40123 Bologna, Italy. plazzi@neuro.unibo.it
Abstract:
We describe a polysomnographic observation of the acute phase of the alcohol withdrawal syndrome, characterized by an alteration of the sleep-wake cycle and by the absence of non-rapid eye movement sleep. An atypical transitional state between rapid eye movement sleep and wake with hallucinations and enacting-dream behaviors represented the sole sleep pattern. Analogies of alcohol withdrawal syndrome with fatal familial insomnia and Morvan's fibrillary chorea suggest a common pathophysiological mechanism in these conditions.
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