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Naringenin derivatives as anti-atherogenic agents
Sangku Lee1, Chul-Ho Lee, Surk-Sik Moon
1Korea Research Institute of Bioscience and Biotechnology, 52 Oun, Yusong, Daejon 305-333, Republic of Korea.
Bioorganic & Medicinal Chemistry Letters
|November 1, 2003
Abstract:
Two classes of naringenin derivatives were evaluated for anti-atherogenic activity. Naringenin 7-O-oleic ester (2) and naringenin 7-O-cetyl ether (3) inhibited the formation of aortic atherosclerotic lesions in high cholesterol-fed rabbits.