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Significant elevation of urinary trypsin inhibitor in patients with brain contusion--a preliminary report
Keiichi Sakai1, Hiroshi Okudera, Kazuhiro Hongo
1Department of Neurosurgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, Japan. skeiichi@hsp.md.shinshu-u.ac.jp
Abstract:
Urinary trypsin inhibitor (UTI) is a protease inhibitor, which is produced in the liver. The correlation between UTI level and head injury has not been evaluated. This study was designed to investigate UTI levels in patients with severe head injury. We measured UTI in the urine of patients with brain contusion. UTI was significantly higher in those patients compared to the control group. The results suggest that UTI may be useful for assessing the severity of head injury and also as a treatment marker in patients with brain contusion.
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