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Updated: Aug 30, 2026

Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
Published on: November 14, 2013
Impaired hypothalamic endocrine function in neuroacanthocytosis
P E Kontoleon1, I Ilias, A Matsouka
1Second Endocrine Department, Alexandra General Hospital, 8 Ofiountos Street, Athens, Greece. pangr@hol.gr
Abstract:
Two sisters aged 28 and 26, suffering from neuroacanthocytosis (NA), had hypothyroidism and showed a flat growth hormone (GH) response to the insulin tolerance test. GH-releasing hormone (GHRH) administration resulted in a normal GH response in the older sister and a partial GH response in the younger sister. A pathological process--attributable to NA--can be suggested, leading to impaired hypothalamic function, but sparing the pituitary.
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