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[Changes of endocrine hormones during -6 degrees head down bed rest in human]
Li-xin Liang1, Zhen-xiu Liu, Yu-min Wan
1Institute of Space Medico-Engineering, Beijing, China.
Objective:
To investigate changes of endocrine hormones during 7 d head down bed rest (HDBR).
Method:
Six healthy male volunteers served as the subjects and experienced 7 d -6 degrees HDBR. Urine was collected from 6:00-22:00 and from 22:00-6:00. Serum was collected 48 h before HDBR, 48 h and 120 h during HDBR. Then the endocrine indices in urine and serum were determined.
Result:
1) The levels of serum CORT and ALD increased at 48 h during HDBR, while serum T3, T4, TP, UN decreased but they all recovered to normal at 120 h during HDBR. 2) The level of urine CORT, ALD and NE reached its peak in 24-48 h, and then gradually decreased to normal level.
Conclusion:
The endocrine indices in serum and urine changed in the early period but returned to normal level gradually with the proceeding of HDBR.