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Markers of loss of control of hypertension
Richard Ian Casson1, Will D King, Noah Marshall S Godwin
1Department of Family Medicine, Queen's University, Kingston, Ont. ric@post.queensu.ca
Insights
Medication adherence, higher income, and life stress are key factors impacting blood pressure (BP) control in patients with hypertension. Poor adherence and stress significantly increase the risk of elevated BP.
Area of Science:
- Cardiology
- Public Health
- Clinical Medicine
Background:
- Essential hypertension is a prevalent chronic condition requiring ongoing management.
- Maintaining controlled blood pressure (BP) is crucial for preventing cardiovascular complications.
- Identifying factors contributing to loss of BP control is vital for effective patient care.
Purpose of the Study:
- To determine predictors of uncontrolled hypertension in adults previously managed with medication.
- To investigate the association between socioeconomic factors, lifestyle, and BP control.
- To identify markers associated with the loss of hypertension control.
Main Methods:
- A longitudinal study involving 385 adults with essential hypertension.
- Patients were monitored for 18 months with repeated blood pressure measurements.
- Questionnaires assessed medication adherence, life stress, and socioeconomic status.
Main Results:
- Higher income correlated with increased diastolic BP.
- Poor medication adherence and elevated life stress were linked to increased systolic BP.
- Life stress doubled the risk of exceeding BP thresholds, indicating a significant impact on hypertension control.
Conclusions:
- Medication adherence, higher income, and life stress are significant factors associated with elevated BP.
- These factors are crucial for understanding and managing the loss of control in previously treated hypertension.
- Targeting these areas may improve long-term hypertension management and patient outcomes.
Objective:
To identify markers for loss of control of hypertension.
Design:
Questionnaire administered to patients who had been monitored for 18 months and had had their blood pressure (BP) measured many times.
Setting:
Fifty family practices in southeastern Ontario.
Participants:
Three hundred eighty-five adults with essential hypertension that was initially stable and controlled by medication.
Main Outcome Measures:
Change in BP (from baseline to mean of three measurements over 18 months) and proportion of patients with BP exceeding threshold values at most follow-up visits.
Results:
Higher income was associated with an increase in diastolic BP; poor adherence to medication regimens and higher life stress were associated with increases in systolic BP Stress also led to a twofold increase in risk of exceeding BP thresholds. Other factors under study were not related to loss of control.
Conclusion:
Adherence to medication regimens, higher income, and life stress were the only factors associated with elevated BP or loss of control in previously controlled hypertension.
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