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Evolution of pericentromeric heterochromatin of human X chromosome
1Division of Genetics, Long Island College Hospital, SUNY Health Science Center, Brooklyn 11201.
Genetica
|January 1, 1992
Abstract:
An unusual large heterochromatic segment around the pericentromeric region of the X-chromosome is reported. In normal circumstances, the pericentromeric region of the X-chromosome is negative by the restriction endonuclease AluI/Giemsa technique. However, this unusual X-chromosome was found to have AluI resistant (positive) chromatin. The evolution of extra heterochromatin is a postzygotic event as substantiated by the presence of a normal cell line.