Related Experiment Videos
Long term follow up after elective percutaneous coronary intervention for unprotected non-bifurcational left main
B R G Brueren1, J M P G Ernst, M J Suttorp
1Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands. brg_brueren@hotmail.com
Insights
Percutaneous coronary intervention (PCI) for left main coronary artery (LMCA) stenosis is generally not recommended. However, elective PCI of the non-bifurcational LMCA proved safe and effective in highly experienced centers.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Surgery
Background:
- Percutaneous coronary intervention (PCI) for left main coronary artery (LMCA) stenosis is typically contraindicated, with coronary artery bypass graft surgery (CABG) preferred per guidelines.
- PCI of the LMCA is reserved for exceptional circumstances.
Purpose of the Study:
- To analyze outcomes of patients undergoing PCI of the unprotected LMCA.
- To evaluate the safety and efficacy of elective PCI for non-bifurcational LMCA stenosis.
Main Methods:
- Retrospective analysis of 71 patients who underwent elective PCI for non-bifurcational LMCA stenosis between 1991 and 2001.
- Procedures included balloon angioplasty and stenting.
- Average follow-up was 43 months.
Main Results:
- The one-year survival rate was 98.6%.
- Annual mortality rate was 2.5%, with most deaths due to non-cardiac causes.
- Coronary artery bypass graft surgery was required in 18.3% of patients during follow-up.
Conclusions:
- Elective PCI of the non-bifurcational LMCA can be performed safely at experienced centers when patient anatomy is suitable.
- PCI offers a viable alternative to CABG in selected LMCA stenosis cases.
Background:
According to the American College of Cardiology/American Heart Association guidelines, percutaneous coronary intervention (PCI) for left main coronary artery (LMCA) stenosis is contraindicated and coronary artery bypass graft surgery (CABG) is preferred. However, PCI of the LMCA is performed under exceptional circumstances.
Objective:
To analyse the data of patients who underwent PCI of the unprotected LMCA in St Antonius Hospital, Nieuwegein, Netherlands.
Results:
In a database of 17 683 PCI procedures, 71 patients (0.4%) were found with non-bifurcational LMCA stenosis who underwent an elective PCI between 1991 and 2001. Ages ranged from 26.7-86.5 years. Severe concomitant disease was the most frequent argument in favour of PCI instead of CABG. PCI consisted of only balloon angioplasty in 23 cases (32.4%). A stent was used in 46 cases (64.4%). Average follow up was 43 months (range 0-121 months). One patient died one day after the procedure. The total one year survival rate was 98.6% (70/71). Seven patients died during the follow up period, mostly because of non-cardiac reasons. The annual mortality rate was 2.5%. Recurrent elective percutaneous transluminal coronary angioplasty for restenosis of the LMCA was performed in one patient (1.4%) six weeks after the initial procedure. CABG was required in 13 patients (18.3%) throughout the follow up period.
Conclusion:
These results suggest that at highly experienced centres, elective PCI of the non-bifurcational LMCA can be performed safely where the anatomy is suitable.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome III: Diagnostic Studies
Cardiac Catheterization III: Left Heart Catheterization
Angina IV: Management