Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Urinary bladder hyperreflexia: a rat animal model.

Hassan Shaker1, Mohammed Sherif Mourad, Mohammed Hatem Elbialy

  • 1Urology Department, Ain Shams University, Cairo, Egypt. hassanshaker@link.net

Neurourology and Urodynamics
|November 5, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sixteen Years of Multinational Experience in Female Genital Fistula Repair: Integrating Traditional and Innovative Surgical Approaches Across 12 Countries.

Neurourology and urodynamics·2026
Same author

Combination of pregabalin and Amitriptyline in management of chronic idiopathic pain following penile prosthesis implantation: a pilot study.

Basic and clinical andrology·2024
Same author

Predictive urinary RNA biomarkers of kidney injury after extracorporeal shock wave lithotripsy.

World journal of urology·2022
Same author

Effect of perioperative selective alpha-1 blockers in non-stented ureteroscopic laser lithotripsy for ureteric stones: a randomized controlled trial.

Central European journal of urology·2021
Same author

Re: A prototype non-invasive urodynamic test to estimate voiding reserve in normal adult males. By Shafik Shoukry, Mostafa Elmissiry, Ahmed Abulfotooh, Ahmed Moussa, Wally Mahfouz, Waleed Dawood, Aly Abdel-Karim and Mohamed Hassouna.

Arab journal of urology·2019
Same author

Fibrin glue as a sealant in stentless laparoscopic pyeloplasty: A randomised controlled trial.

Arab journal of urology·2019
Same journal

Sacral Neuromodulation in the Management of Refractory Pediatric Lower Urinary Tract Dysfunction.

Neurourology and urodynamics·2026
Same journal

Response to the Letter to the Editor on "Effect of Acupressure on Anxiety, Embarrassment, and Procedural Fear in Patients Undergoing Urodynamic Testing: Randomized Controlled Study".

Neurourology and urodynamics·2026
Same journal

Response to the Letter to the Editor on "Effect of Acupressure on Anxiety, Embarrassment, and Procedural Fear in Patients Undergoing Urodynamic Testing: Randomized Controlled Study".

Neurourology and urodynamics·2026
Same journal

The Importance of Video Urodynamics in Selected Oligo-Anuric Patients Awaiting Renal Transplantation.

Neurourology and urodynamics·2026
Same journal

Prior Authorization for Sacral Nerve Stimulation in the Era of WISeR: Evaluation of U.S. Payer Coverage Policies.

Neurourology and urodynamics·2026
Same journal

Advancing Personalized Care for Neurogenic Bladder: The Case for Continent Urinary Diversion.

Neurourology and urodynamics·2026
See all related articles

This study presents a standardized rat model for bladder hyperreflexia following spinal cord injury. The model mimics clinical conditions, offering a cost-effective tool for studying neurogenic bladder dysfunction.

Area of Science:

  • Neuroscience
  • Urology
  • Animal Models

Background:

  • Bladder hyperreflexia is a common complication following spinal cord injury.
  • Existing animal models may not fully replicate the clinical course of this condition.

Purpose of the Study:

  • To standardize a rat model for studying bladder hyperreflexia after suprasacral spinal cord transection.
  • To establish a reliable and reproducible animal model for research.

Main Methods:

  • 26 female Sprague-Dawley rats underwent T10 spinal cord transection.
  • Cystometrograms (CMG) were performed at 24 hours and 3 weeks post-spinalization.
  • Data were compared to six normal control rats.

Main Results:

Related Experiment Videos

  • All rats developed consistent bladder hyperreflexia after an initial spinal shock phase.
  • Expressed urine volume decreased, plateauing at 1 week post-injury.
  • An attrition rate of 27.3% was observed, primarily due to self-inflicted injuries.

    • Conclusions:

    • This rat model effectively replicates clinical bladder hyperreflexia and its typical progression.
    • The model's low cost and ease of maintenance make it valuable for research into neurogenic bladder disorders.