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Updated: Aug 30, 2026

A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
Three-dimensional transvaginal sonography of interstitial pregnancy
Luis A Izquierdo1, M Catherine Nicholas
1Department of Obstetrics and Gynecology, Division of Diagnostic Ultrasound, University of Miami School of Medicine, Jackson Memorial Hospital, 1611 Northwest 12th Avenue, Miami, Florida 33136, USA.
Abstract:
We describe the case of a 33-year-old pregnant woman, gravida 1 para 0, who was referred to us with a presumptive diagnosis of an interstitial pregnancy. The patient had had amenorrhea for 7 weeks and had previously undergone myomectomy. Two-dimensional sonographic examination revealed a gestational sac located outside the uterine cavity but could not define its exact anatomic position. Using transvaginal 3-dimensional sonography, we were able to correctly depict the sac, which was located where the fallopian tube crossed the uterine horn. We performed a cornual resection, during which the diagnosis of interstitial pregnancy was confirmed. The use of 3-dimensional sonography in this patient's case thus led to appropriate early treatment and avoidance of possible subsequent morbidity.
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