Perfusion lung scan in tropical pulmonary eosinophilia

Perfusion lung scan using macroaggregate of human serum albumin tagged with I131 was done in 7 patients with tropical pulmonary eosinophilia (TPE). In the 3 untreated patients perfusion defect of varying degree could be noticed, whereas in 4 other patients with history of chronic illness and previous treatment with multiple courses of diethylcarbamazine the lung scan was normal. Possible pathophysiology in light of above findings in TPE is discussed.