Related Experiment Video
Updated: Aug 30, 2026

An Ex Vivo Explant Model for Studying Glial Interactions in the Mouse Retina
Published on: July 15, 2025
Exudative retinal detachment due to small noncalcified retinal astrocytic hamartoma
Tamara R Vrabec1, James J Augsburger
1Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19129, USA. TRVRDMD@aol.com
Purpose:
To report a case of exudative retinal detachment due to small noncalcified retinal astrocytic hamartoma and review pertinent literature.
Design:
Case report and review of literature.
Methods:
Clinical examination, fluorescein angiography, optical coherence tomography, and laser treatment were performed.
Results:
Exudative macular detachment caused by a small noncalcified retinal astrocytic hamartoma confirmed by optical coherence tomography regressed completely after laser therapy. Visual acuity improved only slightly because lamellar macular thinning developed after subretinal fluid and macular exudates resolved.
Conclusions:
Small noncalcified, parafoveal retinal astrocytic hamartomas may cause macular retinal detachment. Optical coherence tomography may aid in the diagnosis of the tumor. Argon laser photocoagulation may induce tumor regression and resolution of exudative detachment. Final visual acuity may be limited in some cases.
Related Concept Videos
Diabetic Retinopathy
Glaucoma: Overview
Anatomy of the Eyeball
