Neither perceived job stress nor individual cardiovascular reactivity predict high blood pressure

Jean Pierre Fauvel1, Ignasse M'Pio, Pierre Quelin

  • 1Département de Néphrologie et d'Hypertension artérielle, Hôpital E Herriot, 69437 Lyon, France. jean-pierre.fauvel@chu-lyon.fr

Insights

High job strain and cardiovascular reactivity to stress do not predict future high blood pressure (BP) in healthy adults. This 5-year study found no increased hypertension risk in individuals with high job strain or high BP stress reactivity.

Area of Science:

  • Cardiovascular Health
  • Occupational Health
  • Hypertension Research

Background:

  • Previous research indicated a link between high job strain and elevated diastolic blood pressure (DBP) during work hours.
  • The influence of professional strain perception and cardiovascular reactivity on long-term blood pressure (BP) progression remained unclear.

Purpose of the Study:

  • To evaluate the long-term impact of perceived professional strain and cardiovascular reactivity to mental stress on the development of hypertension.
  • To assess whether high job strain (HS) or high BP stress reactivity (HR) are significant risk markers for future hypertension in healthy adults.

Main Methods:

  • A cohort of 292 healthy adults was followed for 5 years to track progression to hypertension (defined by specific SBP or DBP increases).
  • Subjects were categorized into high-strain (HS) and non-high-strain (NHS) groups, and high-reactivity (HR) and non-high-reactivity (NHR) groups for comparison.
  • Kaplan-Meier survival analysis and end-of-follow-up 24-hour ambulatory BP measurements were utilized.

Main Results:

  • Hypertension developed in 31.8% of the subjects over the 5-year follow-up period.
  • Neither the high-strain group nor the high-reactivity group showed an increased incidence of hypertension compared to their respective control groups.
  • End-of-study ambulatory BP levels were similar between the HS and NHS groups, and between the HR and NHR groups.

Conclusions:

  • Perceived high job strain and high cardiovascular reactivity to mental stress do not appear to be major predictors of future high blood pressure in healthy young adults.
  • Factors such as age, alcohol consumption, salt intake, BMI, and occupation did not confound these findings.

Related Concept Videos

Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Factors affecting Blood pressure01:28

Factors affecting Blood pressure

Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
Blood Pressure01:30

Blood Pressure

Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the diastolic...
Blood Pressure01:24

Blood Pressure

The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
Antihypertensive Drugs: Action of β1 Blockers01:17

Antihypertensive Drugs: Action of β1 Blockers

β1-receptors are primarily located in the heart and kidneys. In cardiac myocytes, these receptors interact with neurotransmitters released by the sympathetic nervous system during heightened activity or danger. As a result, β1-receptors get activated, initiating a series of biochemical processes. Excessive activation of beta receptors due to chronic stress can abnormally increase heart rate and contractility, resulting in high blood pressure or hypertension. To counteract this, β1-blockers...