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Constituents from the stems of Goniothalamus griffithii
Qing Mu1, Wei Dong Tang, Ruo Yan Liu
1Phytochemistry Laboratory, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P. R. China. muqing2000@yahoo.com
Abstract:
A new cyclopeptide, grifficyclocin A (1), and a new aporphine alkaloid, griffinin (2) were isolated together with two known styryllactones from the stems of Goniothalamus griffithii. Their structures were identified spectroscopically and chemically. Among them, the griffinin (2) was isolated as the enol form in two tautomers, and the two known styryllactones, goniothalamin (3) and 8- O-acetylgoniotriol (4), showed selective in vitro antitumor activities.
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