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Updated: Aug 30, 2026

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
Published on: July 30, 2009
Functional magnetic resonance imaging in pediatrics
M Wilke1, S K Holland, J S Myseros
1Imaging Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA. Marko.Wilke@med.uni-tuebingen.de
Insights
Functional magnetic resonance imaging (fMRI) is a non-invasive technique to assess brain function in children. This review highlights its applications, challenges, and benefits in pediatric populations, showing great promise for research and clinical use.
Area of Science:
- Neuroscience
- Medical Imaging
Background:
- Functional magnetic resonance imaging (fMRI) non-invasively assesses human brain function by detecting blood flow changes.
- Pediatric neuroimaging presents unique challenges and considerations compared to adult studies.
Purpose of the Study:
- To review the background and various aspects of performing fMRI in the pediatric age group.
- To provide an overview of current and future applications of pediatric fMRI.
- To discuss typical problems, pitfalls, and benefits associated with pediatric fMRI.
Main Methods:
- Review of existing literature on pediatric functional magnetic resonance imaging.
- Discussion of technical considerations and challenges specific to pediatric fMRI acquisition.
- Analysis of applications and outcomes reported in pediatric fMRI studies.
Main Results:
- fMRI can be successfully implemented in children.
- Specific challenges in pediatric fMRI include motion artifacts and subject cooperation.
- Benefits include non-invasive assessment of brain activity and connectivity in developing brains.
Conclusions:
- Functional magnetic resonance imaging (fMRI) is a viable and promising tool for pediatric research and clinical applications.
- Careful consideration of age-specific factors is crucial for successful pediatric fMRI.
- Pediatric fMRI holds significant potential for advancing our understanding of child brain development and disorders.
Abstract:
Functional magnetic resonance imaging (fMRI) allows non-invasive assessment of human brain function in vivo by detecting blood flow differences. In this review, we want to illustrate the background and different aspects of performing functional magnetic resonance imaging (fMRI) in the pediatric age group. An overview over current and future applications of fMRI will be given, and typical problems, pitfalls, and benefits of doing fMRI in the pediatric age group are discussed. We conclude that fMRI can successfully be applied in children and holds great promise for both research and clinical purposes.
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