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Double parathyroid carcinoma
Kaori Kameyama1, Hiroshi Takami
1Division of Diagnostic Pathology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.
Endocrine Journal
|November 6, 2003
Summary
This case report details a rare instance of double parathyroid carcinoma affecting both the left and right parathyroid glands. Surgical removal of both tumors successfully normalized high parathyroid hormone levels.
Area of Science:
- Endocrinology
- Surgical Oncology
- Pathology
Background:
- Parathyroid carcinoma is an exceptionally rare endocrine malignancy.
- Bilateral parathyroid tumors are uncommon, often presenting diagnostic challenges.
Observation:
- A 67-year-old male presented with bilateral parathyroid masses, hypercalcemia, and elevated parathyroid hormone (PTH).
- Preoperative imaging suggested a parathyroid adenoma on the left and potential papillary thyroid carcinoma or parathyroid carcinoma on the right.
Findings:
- Histological examination confirmed both resected tumors as parathyroid carcinoma.
- This represents the first documented case of histologically confirmed double parathyroid carcinoma.
Implications:
- Highlights the importance of thorough histological evaluation for bilateral parathyroid masses.
- This rare presentation expands the understanding of parathyroid carcinoma incidence and management.