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Updated: Aug 30, 2026

An Ex Vivo Chicken Primary Bursal-cell Culture Model to Study Infectious Bursal Disease Virus Pathogenesis
Published on: October 4, 2018
Aspects of the innate and adaptive immune responses to acute infections with BVDV
L S Brackenbury1, B V Carr, B Charleston
1Institute for Animal Health, Compton, Newbury, RG20 7NN, Berkshire, UK.
Abstract:
The immune response can be divided into innate and adaptive components that synergise to effect the clearance of pathogens. Recently, it has been realised that these arms of the immune system do not act independently, the magnitude and quality of the adaptive response is dependent on signals derived from the innate response. Here, we review the innate immune responses to bovine viral diarrhoea virus infections of cattle and relate these changes to immunosuppression and the subsequent development of the adaptive immune response.
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