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Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
Published on: July 25, 2013
A novel fingerprint for the characterization of protein folds
1Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, New York, NY 10029, USA. mezei@inka.mssm.edu
Abstract:
A novel fingerprint, defined without the use of distances, is introduced to characterize protein folds. It is of the form of binary matrices whose elements are defined by angles between the C=O direction, the backbone axis and the line connecting the alpha-carbons of the various residues. It is shown that matches in the fingerprint matrices correspond to low r.m.s.d.
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