Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Models of Health Promotion and Illness Prevention I01:25

Models of Health Promotion and Illness Prevention I

A model is a theoretical way to understand a concept or an idea. Models can overcome barriers to health regardless of diverse economic and cultural backgrounds. In addition, models make the task easier by providing different ways to approach complex issues. There are two major health promotion models: the health belief model and the health promotion model.
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
Models of Health Promotion and Illness Prevention II01:18

Models of Health Promotion and Illness Prevention II

The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results from...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
What is an Experiment?01:12

What is an Experiment?

An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The...
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of acute exercise on inflammatory and metabolic biomarkers in women: a randomized controlled trial.

NPJ breast cancer·2025
Same author

Achieving Healthy Weights for Improving Breast Cancer Prognosis.

JAMA oncology·2025
Same author

In Motion: Experimental Evidence on Exercise and Breast Cancer in Women and Mice.

Clinical cancer research : an official journal of the American Association for Cancer Research·2025
Same author

Generalized Linear Models with Covariate Measurement Error and Zero-Inflated Surrogates.

Mathematics (Basel, Switzerland)·2024
Same author

Diet Matters in Breast Cancer Prognosis: Clinical Trial Evidence and Questions.

Clinical cancer research : an official journal of the American Association for Cancer Research·2023
Same author

Exploring anxiety as an influencing factor of the impact of exercise and mind-body prehabilitation on cognitive functioning among women undergoing breast cancer surgery.

Journal of psychosocial oncology·2023

Related Experiment Video

Updated: Jul 21, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Intervention studies in exercise and cancer prevention.

Anne McTiernan1

  • 1Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA. amctiern@fhcrc.org

Medicine and Science in Sports and Exercise
|November 6, 2003
PubMed
Summary

Exercise intervention studies, including randomized clinical trials, are crucial for understanding physical activity

Area of Science:

  • Exercise physiology
  • Cancer biology
  • Preventive medicine

Background:

  • Physical activity is linked to cancer prevention, but intervention studies are needed to clarify mechanisms.
  • Understanding how exercise impacts cancer biomarkers is key to developing effective prevention strategies.

Purpose of the Study:

  • To evaluate the role of exercise randomized clinical trials and intervention studies in defining the relationship between physical activity and cancer prevention.
  • To synthesize evidence from intervention studies on exercise's effects on cancer-related biomarkers.

Main Methods:

  • Systematic review and summarization of data from published randomized clinical trials.
  • Inclusion of other intervention studies investigating exercise and cancer biomarkers.

More Related Videos

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
09:19

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice

Published on: February 2, 2019

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults
06:13

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults

Published on: December 1, 2023

Related Experiment Videos

Last Updated: Jul 21, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
09:19

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice

Published on: February 2, 2019

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults
06:13

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults

Published on: December 1, 2023

Main Results:

  • Limited intervention studies directly assess exercise's impact on cancer biomarkers.
  • Exercise interventions show effects on sex hormones (relevant to breast and endometrial cancer), insulin, insulin-like growth factor, and immune function.
  • Ongoing randomized clinical trials are further investigating exercise's effects on cancer biomarkers.

Conclusions:

  • Randomized clinical trials offer valuable insights into how exercise interventions influence cancer biomarkers.
  • Evidence supports the role of exercise in modulating factors relevant to cancer prevention.