Related Experiment Video
Updated: Aug 30, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
Published on: August 2, 2022
Metastatic breast cancer: overview of treatment
S M Ali1, H A Harvey, Allan Lipton
1M S Hershey Medical Center, Hershey, PA, USA. Suhail.Ali@med.va.gov
Abstract:
Patients with metastatic breast cancer have a median survival of 2 to 3 years. Twenty percent of the patients who present with bone-only metastasis will be alive at 5 years from diagnosis. Current therapies are aimed at improving the quality of life, symptom control, and prolongation of survival. Newer endocrine and chemotherapeutic drugs are available to the medical oncologist for care of patients with metastatic breast cancer. We will briefly review the new advances in the treatment of metastatic breast cancer.
Insights
Metastatic breast cancer patients face a grim prognosis, with survival typically 2-3 years. Advances in endocrine and chemotherapy offer new hope for improving quality of life and prolonging survival for these patients.
Area of Science:
- Oncology
- Medical Therapeutics
Background:
- Metastatic breast cancer (MBC) presents a significant survival challenge, with a median survival of 2-3 years.
- A subset of patients with bone-only metastasis shows a 5-year survival rate of 20%.
Purpose of the Study:
- To review recent advancements in the treatment of metastatic breast cancer.
- To highlight new therapeutic options for oncologists managing MBC.
Main Methods:
- Literature review of current and emerging treatments for metastatic breast cancer.
- Analysis of the impact of new endocrine and chemotherapeutic agents.
Main Results:
- New endocrine and chemotherapeutic drugs are expanding treatment options for MBC.
- These newer agents aim to improve patient quality of life and survival outcomes.
Conclusions:
- Ongoing research and development are crucial for improving MBC patient outcomes.
- The integration of novel therapies holds promise for better disease management.
Related Concept Videos
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Treatment Resistent Cancers
Targeted Cancer Therapies
There are several types of targeted therapies against specific...

